منابع مشابه
Fluconazole–malonic acid (1/1)
Co-crystallizaton of the anti-fungal drug fluconazole [2-(2,4-difluoro-phen-yl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol] with malonic acid in acetonitrile solution resulted in the formation of the title 1:1 co-crystal, C13H12F2N6O·C3H4O4. The geometry around the central fluconazole atom is distorted tetrahedral. The dihedral angles between the triazole rings and the fluorinated phenyl ring a...
متن کاملAmmonium sulfate – malonic acid aerosols
A study of the phase transition behavior of mixed ammonium sulfate – malonic acid aerosols C. F. Braban and J. P. D. Abbatt Centre for Atmospheric Sciences, Department of Chemistry, Lensfield Road, University of Cambridge, Cambridge, CB2 1EW, UK Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada Received: 22 March 2004 – Accepted: 3 May 2004 – Published: 2 June 2004 Co...
متن کاملOscillatory Oxidation of Malonic Acid by Bromate
In earlier communications we described the re sults of an investigation of the main products of the oscillating oxidation of malonic acid by bromate 1. The products were identified as monobromomalonic acid, dibromoacetic acid and C02 . Also, the relative quantities of the two organic products were deter mined. Current hypothesis on the mechanism of the reac tion pathway under oscillating con...
متن کاملDegradation of malonic acid by rat tissues.
In past years, malonate has been extensively used in mammalian systems in vitro as an inhibitor of the citric acid cycle with very little attention given its metabolism per se. Lifson and Stolen (1) demonstrated the conversion of V-labeled malonate to carbon dioxide in the intact mouse. Later, Lee and Lifson (2) found that the administration to rats of doses of U3-labeled malonate at an inhibit...
متن کاملRadioiodinated Phenylalkyl Malonic Acid Derivatives as pH-Sensitive SPECT Tracers
INTRODUCTION In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of apoptosis. METHODS 2-(4-[(123)I]iodophenethyl)-2-methylmalonic acid (IPMM), 2-(4-[(123)I]iodophenethyl)-malonic acid (IPM), 2-(4-[(123)I]i...
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ژورنال
عنوان ژورنال: J. Chem. Soc., Trans.
سال: 1895
ISSN: 0368-1645
DOI: 10.1039/ct8956701002